Human basophil degranulation test in diagnosis of hydatidosis.
نویسندگان
چکیده
Protein and energy malnutrition and iron-deficiency anaemia are widespread among preschool children in India. Because of a poor antibody response in severely malnourished children admitted to hospital it has been suggested that mass vaccination programmes would not be effective in populations where malnutrition is widespread. Earlier studies by this institute, however, have shown that most children in the community who suffer from mild or moderate protein and energy malnutrition respond well to conventional immunisation programmes.25 Our present findings show that antibody production is also unaffected by iron deficiency. Thus conventional immunisation programmes may be effective even in undernourished communities.
منابع مشابه
Application of a modified human enzyme-linked immunosorbent assay kit for diagnosis of hydatidosis in sheep
Cystic hydatid disease (hydatidosis) is one of the most important zoonosis that is caused by the larval stage of Echinococcus granulosus . As its diagnosis by clinical symptoms alone is difficult and confusing, serologic diagnostic techniques are used to confirm the disease. These techniques can also be used for epidemiologic studies. The present study was performed with a commercial human en...
متن کاملThe basophil activation test by flow cytometry: recent developments in clinical studies, standardization and emerging perspectives
The diagnosis of immediate allergy is mainly based upon an evocative clinical history, positive skin tests (gold standard) and, if available, detection of specific IgE. In some complicated cases, functional in vitro tests are necessary. The general concept of those tests is to mimic in vitro the contact between allergens and circulating basophils. The first approach to basophil functional respo...
متن کاملExpansion of a highly sensitive and specific ELISA test for diagnosis of hydatidosis using recombinant EgB8/2 protein
Objective(s): Hydatidosis is a zoonotic infection and endemic in Iran. Due to the serological cross-reactivity (of sera) with other parasitic infection, diagnosis of hydatid cyst is considered to be problematic. In this regard, application of recombinant antigens improves serological diagnosis for human hydatidosis. Here, we present an ELISA test based on B8/2 recombinant antigen of Echinococcu...
متن کاملEvidence of an immediate hypersensitivity mechanism in systemic lupus erythematosus.
In 30 patients with systemic lupus erythematosus the number of a circulating basophils was countered in different stages of activity. An inverse correlation was found between the absolute basophils count and anti-DNA antibodies and presumptive circulating immune complexes (as judged by polyethylene glycol precipitation of serum). A positive correlation was found between the absolute basophil co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British medical journal
دوره 280 6226 شماره
صفحات -
تاریخ انتشار 1980